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Название: Functional Metabolism: Regulation and Adaptation
Автор: Kenneth B. Storey
Издательство: Wiley-Liss
Год: August 16, 2004
ISBN: 047141090X / 978-0471410904
Страниц: 616
Язык: English
Формат: pdf
Размер: 62 Mb

In the post-genome era, questions concerning gene products, enzymes, and metabolism are returning to the forefront of life science research. Genetic information on its own does not fully account for an enzyme’s kinetic and regulatory properties or for the behavior of the enzymes within its particular cellular milieu. Unanswered questions about the regulation, integration, and adaptation of metabolism have led to a resurgence of interest in protein, enzymological, and metabolic research for understanding biological processes.

Functional Metabolism: Regulation and Adaptation provides a comprehensive survey of metabolism. It includes an in-depth examination of the regulation of carbohydrates, lipids, and amino acids, and approaches to the study of enzyme regulation, signal transduction, and control of transcription and translation. The contributors--an internationally recognized group of researchers--also cover:
The metabolic basis of diabetes, obesity, and blood disorders
Oxidative stress and antioxidant defenses in health and disease
Novel perspectives on biochemical adaptation to environmental stress
Application of metabolic knowledge to developments in organ preservation and understanding the origin of life

From the basics of metabolic regulation and adaptation to the latest relevant advances in the genetic, proteomic, and enzymatic basis of how cells regulate their functions, Functional Metabolism: Regulation and Adaptation offers the most exhaustive treatment of the subject currently available. It is an essential text for students and practitioners in biochemistry, cell and molecular biology, and biomedicine.

"What distinguishes this book form some others is the thoroughness and breadth of its treatment of subjects, its authority, its academic approach, and the sense of excitement that it engenders." (Annals of Biomedical Engineering, June 2006)

"...is true to the fundamentals and recent developments in metabolic research and points the way to future, deeper convergence of metabolism and genetics." (American Journal of Human Biology, July/August 2005)

"…this book offers a wide menu of interesting biology...it is a highly recommended read for anyone interested in integrative biology." (Clinical Biochemistry, June 2005)

"Storey and other contributors...have created an exceptional volume, looking at this process and its effect on living beings." (E-STREAMS, April 2005)

"...valuable reading for students and researchers alike. It established an essential integrative and comparative mentality...and is an encyclopedic source for researchers…" (The Journal of Experimental Biology, March 2005)

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