Color atlas of histopathology of the cervix uteri.Автор:
Gisela Dallenbach-Hellweg, Magnus von Knebel Doeberitz, Marcus J.Trunk.Издательство:
The new edition of this atlas integrates all significant advances made in the past 15 years
in molecular pathology, tumor virology, and genetics of cervical cancer. It emphasizes
the importance of these advances in facilitating its pathological diagnosis and in optimizing
clinical management and prognosis.A new chapter on immunohistochemistry
has been added, which includes refined detection methods, e.g., the overexpression of
p16INK4a as a molecular marker in the early differential diagnosis of premalignant lesions.
The section on etiology and pathogenesis in human papillomavirus-induced
neoplasia has been incorporated to represent new insights into the sequences of cellular
and nuclear deregulation at the molecular level.All chapters have been revised to include
the newest advances and relevant experiences in how to interpret and manage
cervical disease; they are supported by the addition of 35 new microphotographic illustrations.
The tumor nomenclature is adapted to the latest edition of the WHO classification;
the morphology code of the international classification of diseases for oncology
(ICD-O) has been added.We have also updated the list of references by adding recent
Again, the staff of Springer-Verlag deserve our thanks for their patience and skill in
preparing the manuscript and in reproducing the microphotographs.